We use advanced molecular and imaging techniques to investigate how stem cells evolve from healthy to malignant states. We are working to uncover critical mechanisms driving blood cancers and identify new therapeutic targets.
We are focusing on understanding leukemia pathogenesis at the (pre-leukemic) stem cell level
Investigating the role of and leveraging the sugar code on the cell's surface
Identification of novel molecular mechanisms and pathways governing stem cell subclonal heterogeneity, dynamics, and competition
